糖尿病精准管理依赖于对个体血糖动态的全面解析，连续血糖监测（CGM）技术提供了丰富的时序数据，但数据复杂多变、噪声干扰显著，使得传统方法难以准确捕捉复杂的血糖动态。数学与系统科学研究院等多家机构合作研发了持续血糖监测数据预训练模型CGMformer。CGMformer基于Transformer架构，通过自监督学习从大规模的CGM数据中学习个体代谢状态的精准表征，可辅助2型糖尿病的诊断、病程判断和并发症预测，划分非糖尿病人群亚型，预测餐后血糖并为糖尿病患者提供个性化饮食建议。相关工作发表在《国家科学评论》（National Science Review）上。
Publication:
National Science Review, nwaf039, 08 February 2025 https://academic.oup.com/nsr/advance-article/doi/10.1093/nsr/nwaf039/8005967
Author:
CEMS, NCMIS, HCMS, MADIS, Academy of Mathematics and Systems Science, Chinese Academy of Sciences
, Beijing 100190
, China
School of Mathematics, University of Chinese Academy of Sciences, Chinese Academy of Sciences
, Beijing 100049
, China
Department of Endocrinology and Metabolism, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai Key Laboratory of Diabetes Mellitus
, Shanghai 200233
, China
Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences
, Hangzhou 310024
, China
BGI-Research
, Hangzhou 310030
, China
School of Mathematics, South China University of Technology
, Guangzhou 510640
, China
School of Mathematics, South China University of Technology
, Guangzhou 510640
, China
CEMS, NCMIS, HCMS, MADIS, Academy of Mathematics and Systems Science, Chinese Academy of Sciences
, Beijing 100190
, China
School of Mathematics, University of Chinese Academy of Sciences, Chinese Academy of Sciences
, Beijing 100049
, China
CEMS, NCMIS, HCMS, MADIS, Academy of Mathematics and Systems Science, Chinese Academy of Sciences
, Beijing 100190
, China
School of Mathematics, University of Chinese Academy of Sciences, Chinese Academy of Sciences
, Beijing 100049
, China
CEMS, NCMIS, HCMS, MADIS, Academy of Mathematics and Systems Science, Chinese Academy of Sciences
, Beijing 100190
, China
Department of Statistics, Department of Biomedical Data Science, Bio-X Program, Stanford University
, Stanford CA 94305
, USA
CEMS, NCMIS, HCMS, MADIS, Academy of Mathematics and Systems Science, Chinese Academy of Sciences
, Beijing 100190
, China
Department of Computer Science and Engineering, Shanghai Jiao Tong University
, Shanghai 200240
, China
Department of Endocrinology and Metabolism, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai Key Laboratory of Diabetes Mellitus
, Shanghai 200233
, China
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
, Shanghai 200031
, China
Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences
, Hangzhou 310024
, China
Guangdong Institute of Intelligence Science and Technology
, Hengqin, Zhuhai, Guangdong 519031
, China
Pazhou Laboratory (Huangpu)
, Guangzhou, Guangdong 510555
, China
Department of Endocrinology and Metabolism, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai Key Laboratory of Diabetes Mellitus
, Shanghai 200233
, China
CEMS, NCMIS, HCMS, MADIS, Academy of Mathematics and Systems Science, Chinese Academy of Sciences
, Beijing 100190
, China
School of Mathematics, University of Chinese Academy of Sciences, Chinese Academy of Sciences
, Beijing 100049
, China
Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences
, Hangzhou 310024
, China
